Publications
Chithran AV, Allan DW*, O’Connor TP* (2024) Adult expression of the cell adhesion protein Fasciclin 3 is required for the maintenance of adult olfactory interneurons. Journal of Cell Science. Jun 15;137(12):jcs261759. PMID:38934299. * co-corresponding.
Vuilleumier R, Miao M, Medina-Giro S, Ell C-M, Flibotte S, Lian T, Kauwe G, Collins A, Ly S, Pyrowolakis G, Haghighi AP, Allan DW (2022) Dichotomous cis-regulatory motifs mediate the maturation of the neuromuscular junction by retrograde BMP signaling. Nucleic Acids Research. 50 (17), 9748-9764 doi.org/10.1093/nar/gkac730
Ganguly P, Madonsela L, Chao JT, Loewen JR, O’Connor TP, Verheyen EM, Allan DW (2021) A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation. PLoS Genetics. 17:9, e1009774.
Post KL*, Belmadani M*, Ganguly P*, Meili F*, Dingwall R, McDiarmid TA, Meyers WM, Herrington C, Young, BP, Callaghan DB, Rogic S, Edwards M, Niciforovic A, Cau A, Rankin CH, O’Connor TP, Bamji SX, Loewen CJR, Allan, DW, Pavlidis P, Haas K (2020) Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction. Nature Communications 11:1, 1-16.
Berndt AJE, Lian T, Cho RY, Fong JS, Hur SA, Othonos KM, Allan DW (2020) Suboptimization of a cis-regulatory BMP response element confers neuronal subtype-specific gene activation. eLife. 9. e59650.
Vuilleumier R, Lian T, Flibotte S, Khan Z, Fuchs A, Pyrowolakis G, Allan DW. (2019). Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element. Nucleic Acids Research 47 (2), 679-699.
Gabilondo H, Rubio-Ferrera I, Losada-Pérez M, del Saz D, León Y, Molina I, Torroja L, Allan DW, Benito-Sipos J (2018) Segmentally homologous neurons acquire two different terminal neuropeptidergic fates in the Drosophila nervous system. PLoS One13(4): e0194281
Garner SRC, Castellanos MC, Baillie K, Allan DW (2018) Drosophila female-specific Ilp7 motoneurons are generated by Fruitless-dependent cell death in males and by a double-assurance survival role for Transformer in females. Development 145 (1), dev150821
Hegle AP, Frank CA, Berndt AJP, Klose M, Allan DW, Accili EA (2017) The Ih Channel Gene Promotes Synaptic Transmission and Coordinated Movement in Drosophila melanogaster. Frontiers in molecular neuroscience10, 41
ConnellM, ChenH, JiangJ, KuanC-W, FotovatiA, ChuT, HeZ, LengyellTC, LiH, KrollT, LiAM, GoldowitzD, FrappartL, PloubidouA, PatelM, PilarskiLM,SimpsonEM,LangePF, AllanDW, Maxwell CA. (2017) HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. eLife. 6:e28672 DOI: 10.7554/eLife.28672
S Thor, DW Allan (2016) Advances in Understanding the Generation and Specification of Unique Neuronal Sub-types from Drosophila Neuropeptidergic Neurons. Organogenetic Gene Networks, 57-93
Berndt AJ, Tang JC, Ridyard MS, Lian T, Keatings K, Allan DW. (2015) Gene Regulatory Mechanisms Underlying the Spatial and Temporal Regulation of Target-Dependent Gene Expression in Drosophila Neurons. PLoS Genet. 2015 Dec 29;11(12):e1005754
Cowan CM, Quraishe S, Hands S, Sealey M, Mahajan S, Allan DW, Mudher A. (2015) Rescue from tau-induced neuronal dysfunction produces insoluble tau oligomers. Science Reports. Nov 26;5:1719.
Allan DW and Thor S (2015) Transcriptional Selectors, Masters and Combinatorial Codes: Regulatory Principles of Neural Subtype Specification. WIREs Developmental Biology. Wiley Interdiscip Rev Dev Biol. 2015 Apr 8.
Kerr C, Wang Q, Keatings K, Khong A, Allan DW, Yip C, Foster L, and Jan E. (2015) The 5'untranslated region of a novel infectious molecular clone of the dicistrovirus Cricket paralysis virus modulates infection. Journal of Virology. March: 463-15.
Zheng C, Tham CTT, Keatings K, Fan S, Liou AYC , Numata Y, Allan DW and Numata M (2014) Secretory Carrier Membrane Protein (SCAMP) Deficiency Influences Behavior of Adult Flies Front. Cell Dev. Biol. doi: 10.3389/fcell.2014.00064
Garaulet DL, Castellanos MC, Bejarano F, Sanfilippo P, Tyler DM, Allan DW, Sánchez-Herrero E, Lai EC. (2014) Homeotic function of Drosophila Bithorax-complex miRNAs mediates fertility by restricting multiple Hox genes and TALE cofactors in the CNS. Developmental Cell. 29(6):635-48
Castellanos M, Tang CYJ, Allan DW. Female-biased dimorphism underlies a female-specific role for post-embryonic Ilp7-neurons in Drosophila fertility. Development. 140: 3915-3926.
Veverytsa L, Allan DW (2013) Subtype specific neuronal remodeling during Drosophila metamorphosis. Invited Review. Fly. 7(2):78-86
Szabat M, Kieffer TJ, Hoffman BG, Lynn F, Allan DW, Johnson JD (2012) b-Cell maturity and plasticity: Developmental biology meets physiology in the adult pancreas. Diabetes 61: 1365-1371
Veverytsa L and Allan DW (2012) Temporally tuned neuronal differentiation supports the functional remodeling of a neuronal network in Drosophila. Proceedings of the National Academy of Sciences of USA (PNAS) 109 (13): E748–E756
Eade KT, Fancher HA, Ridyard MS, Allan DW (2012) Developmental transcriptional networks are required to maintain neuronal subtype identity in the mature nervous system. PLoS Genetics 8(2): e1002501
Veverytsa, L and Allan DW (2011) Retrograde BMP-signaling controls Drosophila behavior through regulation of a peptide hormone battery. Development. 138(15):3147-5
Cowan CM, Sealey MA, Quraishe S, Targett M-T, Marcellus K, Allan DW and Mudher A (2011). Review. Modelling Tauopathies in Drosophila: insights from the fruit fly. International Journal of Alzheimer’s Disease 2011: 598157 (16 pages).
Eade KT and Allan DW (2009) Neuronal phenotype in the mature nervous system is maintained by target-derived BMP signaling. Journal of Neuroscience 29: 3852-3864.
Allan DW (2008) Review. Combinatorial Codes in Neuronal Specification. The Encyclopedia of Neuroscience. Springer Press. Binder, M.D.; Hirokawa, N.; Windhorst, U.; Hirsch, M.C. (Eds.).
Allan DW, Park D, St. Pierre SE, Taghert PH, Thor S (2005) Regulators acting independently and in combinatorial codes to specify different aspects of neuronal identity. Neuron 45: 689-700.
Miguel-Aliaga I, Allan DW, Thor S (2004) Independent roles of the dachshund and eyes absent genes in the specification of neuropeptidergic cell identity. Development 131(23): 5837-5848.
Allan DW, Pierre SE, Miguel-Aliaga I, Thor S (2003) Specification of neuropeptide cell identity by the integration of retrograde BMP signaling and a combinatorial transcription factor code. Cell 113(1): 73-86.
Allan DW and Thor S (2003) Preview. Together at last. bHLH and LIM-HD regulators cooperate to specify motor neurons. Neuron 38(5): 675-7.